敗血癥是由致病菌侵入血液循環(huán)并在其中生長繁殖，產(chǎn)生毒素而引起的全身性感染，易在人體抵抗力降低的情況下發(fā)生。嚴(yán)重的敗血癥會(huì)威脅病人的重要器官

近日，UBC研究員Keith Walley等人證實(shí)：抑制或減少PCSK9，可能幫助患者身體清除細(xì)菌和真菌的有毒殘余（抗生素抗擊細(xì)菌和真菌后所剩下的廢物）。處理掉感染廢棄物可改善患者的預(yù)后和存活率。

使用PCSK9抑制劑治療嚴(yán)重膿毒癥小鼠，能增加其存活率。由遺傳變異導(dǎo)致PCSK9水平減少的小鼠也表現(xiàn)出敗血癥結(jié)果和存活率得到改善。

XY-EL-H0001c    人α1酸性糖蛋白(α1-AGP)ELISA試劑盒    Human α1-AGP (Alpha-1-Acid Glycoprotein) ELISA Kit
XY-EL-H0002c    人血管緊張素轉(zhuǎn)化酶 (ACE)ELISA試劑盒    Human ACE (Angiotensin I Converting Enzyme) ELISA Kit
XY-EL-H0003c    人激活素A(ACVA)ELISA試劑盒    Human ACVA (Activin A) ELISA Kit
XY-EL-H0004c    人脂聯(lián)素(ADP/Acrp30)ELISA試劑盒    Human ADP/Acrp30 (Adiponectin) ELISA Kit
XY-EL-H0005c    人Agouti相關(guān)蛋白(AgRP)ELISA試劑盒    Human AgRP (Agouti Related Protein) ELISA Kit
XY-EL-H0006c    人血管生成素(ANG)ELISA試劑盒    Human ANG (Angiogenin) ELISA Kit
XY-EL-H0007c    人促血管生成素1(ANG1)ELISA試劑盒    Human ANG1 (Angiopoietin 1) ELISA Kit
XY-EL-H0008c    人促血管生成素2(ANG2)ELISA試劑盒    Human ANG2 (Angiopoietin 2) ELISA Kit
XY-EL-H0009c    人B細(xì)胞活化因子 (BAFF/CD257)ELISA試劑盒     Human BAFF/CD257 (B-Cell Activating Factor) ELISA Kit
XY-EL-H0010c    人腦源性神經(jīng)因子(BDNF)ELISA試劑盒     Human BDNF (Brain Derived Neurotrophic Factor) ELISA Kit
XY-EL-H0011c    人骨成型蛋白2 (BMP-2)ELISA試劑盒     Human BMP-2 (Bone Morphogenetic Protein 2) ELISA Kit
XY-EL-H0012c    人骨成型蛋白4 (BMP-4)ELISA試劑盒     Human BMP-4 (Bone Morphogenetic Protein 4) ELISA Kit
XY-EL-H0013c    人骨成型蛋白7 (BMP-7)ELISA試劑盒     Human BMP-7 (Bone Morphogenetic Protein 7) ELISA Kit
XY-EL-H0014c    人上皮型鈣黏蛋白 (E-Cad)ELISA試劑盒     Human E-Cad (E-Cadherin) ELISA Kit
XY-EL-H0015c    人碳酸酐酶IX (CA9)ELISA試劑盒    Human CA9 (Carbonic Anhydrase IX) ELISA Kit
XY-EL-H0016c    人胱天蛋白酶1(CASP1)ELISA試劑盒    Human CASP1 (Caspase 1) ELISA Kit
XY-EL-H0017c    人半胱天冬酶3(CASP3)ELISA試劑盒    Human CASP3 (Caspase 3) ELISA Kit
XY-EL-H0018c    人組織蛋白酶B(CTSB)ELISA試劑盒    Human CTSB (Cathepsin B) ELISA Kit
XY-EL-H0019c    人組織蛋白酶V(CTSV)ELISA試劑盒    Human CTSV (Cathepsin V) ELISA Kit
XY-EL-H0020c    人單核細(xì)胞趨化蛋白1(MCP-1)ELISA試劑盒    Human MCP-1 (Monocyte Chemotactic Protein 1) ELISA Kit
XY-EL-H0021c    人巨噬細(xì)胞炎性蛋白1α(MIP-1α)ELISA試劑盒    Human MIP-1α (Macrophage Inflammatory Protein 1 Alpha) ELISA Kit 
XY-EL-H0022c    人巨噬細(xì)胞炎性蛋白1β(MIP-1β)ELISA試劑盒     Human MIP-1β (Macrophage Inflammatory Protein 1 Beta) ELISA Kit 
XY-EL-H0023c    人調(diào)節(jié)正常T細(xì)胞表達(dá)和分泌因子(RANTES)ELISA試劑盒     Human RANTES (Regulated On Activation, Normal T-Cell Expressed and Secreted) ELISA Kit 
XY-EL-H0024c    人單核細(xì)胞趨化蛋白3(MCP-3)ELISA試劑盒    Human MCP-3 (Monocyte Chemotactic Protein 3) ELISA Kit
XY-EL-H0025c    人嗜酸粒細(xì)胞趨化因子(ECF/CCL11)ELISA試劑盒    Human ECF/CCL11 (Eosinophil Chemotactic Factor) ELISA Kit
XY-EL-H0026c    人胸腺激活調(diào)節(jié)趨化因子(TARC)ELISA試劑盒    Human TARC (Thymus Activation Regulated Chemokine) ELISA Kit
XY-EL-H0027c    人巨噬細(xì)胞炎性蛋白3α(MIP-3α)ELISA試劑盒    Human MIP-3α (Macrophage Inflammatory Protein 3 Alpha) ELISA Kit 
XY-EL-H0028c    人二級(jí)淋巴組織趨化因子(SLC)ELISA試劑盒    Human SLC (Secondary Lymphoid Tissue Chemokine) ELISA Kit
XY-EL-H0029c    人巨噬細(xì)胞來源的趨化因子(MDC)ELISA試劑盒    Human MDC (Macrophage Derived Chemokine) ELISA Kit
XY-EL-H0030c    人髓樣前體細(xì)胞抑制因子2(MPIF2)ELISA試劑盒    Human MPIF2 (Myeloid Progenitor Inhibitory Factor 2) ELISA Kit
XY-EL-H0031c    人巨噬細(xì)胞炎性蛋白4α(MIP4α)ELISA試劑盒    Human MIP4α (Macrophage Inflammatory Protein 4 Alpha) ELISA Kit
XY-EL-H0032c    人皮膚T細(xì)胞虜獲趨化因子(CTACK)ELISA試劑盒     Human CTACK (Cutaneous T-cell Attracting Chemokine) ELISA Kit
XY-EL-H0033c    人可溶性CD14分子(sCD14)ELISA試劑盒    Human sCD14 (Soluble Cluster of Differentiation14) ELISA Kit
XY-EL-H0034c    人免疫球蛋白E Fc段受體Ⅱ(FcεRⅡ/CD23)ELISA試劑盒     Human FcεRII/CD23 (Receptor II for the Fc Region of Immunoglobulin E) ELISA Kit
XY-EL-H0035c    人白細(xì)胞分化抗原CD40配體(CD40L/TNFSF5)ELISA試劑盒    Human CD40L/TNFSF5 (Cluster of Differentiation 40 Ligand) ELISA Kit
XY-EL-H0036c    人CD163分子(CD163)ELISA試劑盒    Human CD163 (Cluster of Differentiation 163) ELISA Kit
XY-EL-H0037c    人軟骨糖蛋白39(GP39)ELISA試劑盒     Human GP39 (Glycoprotein 39, Cartilage) ELISA Kit
XY-EL-H0038c    人叢生蛋白(CLU)ELISA試劑盒    Human CLU (Clusterin) ELISA Kit
XY-EL-H0039c    人睫狀神經(jīng)營養(yǎng)因子(CNTF)ELISA試劑盒     Human CNTF (Ciliary Neurotrophic Factor) ELISA Kit 

許多制藥公司目前正在開發(fā)PCSK9抑制劑，用以增加對(duì)膽固醇的清除作用，從而降低心血管疾病風(fēng)險(xiǎn)。這就為用PCSK9抑制劑治療感染性患者帶來了可能