胃蛋白酶原1抗體Pepsinogen相關(guān)標(biāo)記     Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP   APC   Biotin  Cy3   Cy5  
 Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   RBITC  
英文名稱    Pepsinogen I    
中文名稱    胃蛋白酶原1抗體    
別    名    PEPA3_HUMAN; PGI; Pepsin A-3; Pepsinogen 3 group I; PEPSINOGEN I--SECOND LOCUS; Pepsinogen-3; PGA3.    
研究領(lǐng)域    細胞生物  免疫學(xué)    
抗體來源    Rabbit    
克隆類型    Polyclonal    
交叉反應(yīng)    Human,     
胃蛋白酶原1抗體Pepsinogen產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-（石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    
分 子 量    35kDa    
細胞定位    細胞漿     
性    狀    Lyophilized or Liquid    
濃    度    1mg/1ml    
免 疫 原    KLH conjugated synthetic peptide derived from human Pepsinogen I    
亞    型    IgG    
純化方法    affinity purified by Protein A    
儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    
保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    
胃蛋白酶原1抗體Pepsinogen產(chǎn)品介紹    background:
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.

Function:
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.

Subcellular Location:
Secreted.

Similarity:
Belongs to the peptidase A1 family.

Gene ID:
643834

Database links:
Entrez Gene: 643834 Human
Omim: 169710 Human
SwissProt: P0DJD8 Human
Unigene: 601055 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.