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當(dāng)前位置:上海博研生物工程研究中心>>科研抗體>>抗體>>Anti-BACH2抗體,轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體-技術(shù)說(shuō)明

Anti-BACH2抗體,轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體-技術(shù)說(shuō)明

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商鋪產(chǎn)品:9977條

所在地區(qū):上海上海市

聯(lián)系人:楊洋 (經(jīng)理)

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博研生物強(qiáng)烈*“Anti-BACH2抗體,轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體-技術(shù)說(shuō)明",品質(zhì)保障,*,提供,實(shí)驗(yàn)無(wú)結(jié)果可免費(fèi)退換?。?/p>

詳細(xì)介紹

Anti-BACH2抗體,轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體-技術(shù)說(shuō)明產(chǎn)品介紹:Members of the small Maf family (MafK, MafF, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors. They dimerize with other proteins and bind DNA to either represse or activate transcription depending on the dimer compositions. BACH1 and BACH2, heterodimerization partners of MafK, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors. BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap ‘n’ collar-type bZip domain but are otherwise divergent. BACH1 appears ubiquitous, whereas BACH2 is restricted to monocytes, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation. BACH2, a 841 amino acid polypeptide, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family. In culture cells, BACH2 is localized to the cytoplasm through its C-terminal cytoplasmic localization signal (CLS). Oxidative stressors aborted the CLS activity and induce nuclear accumulation of BACH2, which mediates nucleocytoplasmic communciation to couple oxidative stress and transcription repression in mammalian cells. BACH2 heterodimerizes with MAZR through its BTB/POZ domain to activate transcription. BACH2 also plays an important role in the regulation of B cell development.

保存條件:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本產(chǎn)品提供僅供研究使用,不用于人類治療或診斷.


產(chǎn)品名稱:Anti-BACH2抗體,轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體-技術(shù)說(shuō)明

產(chǎn)品編號(hào):BYK-12563R

產(chǎn)品規(guī)格:0.1ml/0.2ml

產(chǎn)品價(jià)格:請(qǐng)

性 狀:Lyophilized or Liquid

濃 度:1mg/1ml

亞 型:IgG

貯 存:貯存于-20℃.

抗體來(lái)源:本公司抗體有兔來(lái)源和鼠來(lái)源等

克隆類型:兔來(lái)源為多抗,鼠來(lái)源為單抗

產(chǎn)品類型:一抗

此抗體本公司有單抗和多抗,可用于免疫組化(IHC),免疫印跡(WB),酶聯(lián)免疫(ELISA),IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)(可來(lái)電索取說(shuō)明)

此產(chǎn)品本公司有標(biāo)記的一抗出售,相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記


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