Cat. Number:  Rs-1165R  

Quantity size:  0.1ml/0.2ml （dilute with pH 7.4    0.01 M PBS or diluent of antibody）

 

Background:  Beta-catenin is an adherens junction protein. Adherens junctions （AJs; also called the zonula adherens） are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.

 

 Anti-β-catenin/β-cats抗體說(shuō)明書(shū)

Specificity:      · anti-β-catenin/β-cats is a rabbit monoclonal antibody unconjugated  

                ·specific for β-catenin/β-cats of human, mo, rat, chicken

                ·epitope mapping near the β-catenin/β-cats of human, mo, rat,

chicken

· use for western blotting, elisa, immunoprecipitation  

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG  

· mol wt: 92kDa

 

Application:     ·Western blotting: 1:100-500

· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Optimal working dilutions must be determined by the end user.

 

 

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.