人類表皮生長因子，SIGMA E9644-5×0.2MG
分類 抗體
含量 ≥97 (SDS-PAGE)（％）
產(chǎn)品規(guī)格 SIGMA E9644-5×0.2MG
CAS 62253-63-8
品牌 SIGMA
用途范圍 生物科研
保存溫度 -20℃
英文名稱 Epidermal Growth Factor human-EGF human
供應(yīng)商 上海研伴實(shí)業(yè)有限公司
表皮生長因子 人類 SIGMA E9644-5X0.2MG
recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
· 產(chǎn)品編號：E9644
· 中文名稱：表皮生長因子 人類
· 英文名稱：Epidermal Growth Factor human-EGF human
· 英文別名:EGF LONG® EGF
· CAS號：62253-63-8
· 純度：≥97% (SDS-PAGE)
· 保存溫度：−20 °C
· MDL號：MFCD00132565
訂貨信息：
產(chǎn)品規(guī)格價(jià)格(RMB)
· E9644-0.2MG2,999.88元
· E9644-5X0.2MG13,209.30元
注：此價(jià)格僅供參考，請以SIGMA價(jià)格為準(zhǔn)，優(yōu)惠價(jià)請電詢。
性能描述
Analysis Note
≥98% SDS-PAGE
Biochem/physiol Actions
Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline
Application
Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
General description
Epidermal Growth Factor (EGF) is a small mitogenic polypeptide which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is structurally homologous to human transforming growth factor-α (TGF-alpha), and both exert their actions through EGF receptors. EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells.
EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
法律信息
LONG 注冊商標(biāo) Novozymes Gropep Limited
Other Notes
The biological activity of recombinant, human EGF is measured by its ability to stimulate the mouse fibroblast cell line, BALB/3T3. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.
性質(zhì)
Related Categories | Cancer Research Cell Biology Cell Culture Cell Culture Supplies Cell Signaling and Neuroscience更多... |
Quality Level | PREMIUM |
recombinant | expressed in E. coli |
assay | ≥97% (SDS-PAGE) |
form | lyophilized powder |
potency | 0.08-0.8 ng/mL ED50/EC50 |
total impurities | ≤1 EU/μg endotoxin(EGF) |
suitability | suitable for cell culture |
storage temp. | −20°C |
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人類表皮生長因子，SIGMA E9644-5×0.2MG
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