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武漢紐斯特生物科技有限公司
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更新時間：2024-04-24 15:43:41瀏覽次數(shù)：52次
聯(lián)系我時，請告知來自 環(huán)保在線NFE2L2ProteinR34Qmutant[10447][100ul]CatalogNumber:10447ProductName:NFE2L2ProteinR34QmutantSynonyms:Nuclearfactor(erythroid-derived2)-like2
NFE2L2 Protein R34Q mutant [10447]
[100ul]
| Catalog Number: 10447 |
| Product Name: NFE2L2 Protein R34Q mutant |
| Synonyms: Nuclear factor (erythroid-derived 2)-like 2, Nrf2 |
| Source: Human, recombinant full length, His6-tag |
| Expression Host: E. coli |
| Molecular Weight: 26 kDa |
| Purity: >99% by SDS-PAGE |
| Introduction: NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress. |
| Amino Acid Sequence (1-170) |
| MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSQEVFD FSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL DEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDAL YFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIE SPVFIATNQAQSPETSVA |
| Properties |
| Physical Appearance (form): Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl. |
| Physical Appearance (form): White or clear |
| Concentration: 1 mg/mL |
| Storage: -80°C |
| Preparation Instructions: Adding of 10 mM β-mercaptoethanol or 1 mM DTT into the solution to protect the protein is recommended and using of non-ionic detergents such as n-Dodecyl β-D-maltoside (DoDM) or polyethylene detergents (e.g. C12E10) also help to stabilize the protein. Avoid repeated freezing and thawing. The purity of His-tagged NFE2L2 R34Q was determined by SDS-PAGE and Coomassie Brilliant Blue Staining. |
| References: 1. Moi P et al., Proc. Natl. Acad. Sci. U.S.A. 91 (21): 9926-30. 2. Gold R et al., N. Engl. J. Med. 367 (12): 1098-107. |
| Datasheet: |
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| Anti NFE2L2 Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(E79K) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(D29G) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
| Anti NFE2L2(E79Q) Mouse Monoclonal Antibody | 100 μL | ￥4800 | |
| Anti NFE2L2(L30F) Mouse Monoclonal Antibody | 100 μL | ￥4,800 | |
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