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當(dāng)前位置:上海博研生物工程研究中心>>科研抗體>>抗體>>Anti-Pokemon/ZBTB7抗體,撲克蒙蛋白抗體

Anti-Pokemon/ZBTB7抗體,撲克蒙蛋白抗體

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更新時間:2018-06-07 21:05:41瀏覽次數(shù):221次

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商鋪產(chǎn)品:9977條

所在地區(qū):上海上海市

聯(lián)系人:楊洋 (經(jīng)理)

產(chǎn)品簡介

Anti-Pokemon/ZBTB7抗體,撲克蒙蛋白抗體,規(guī)格0.1ml/0.2ml,提供,:.

詳細(xì)介紹

產(chǎn)品名稱:Anti-Pokemon/ZBTB7抗體,撲克蒙蛋白抗體

產(chǎn)品編號:BYK-10235R

產(chǎn)品規(guī)格:0.1ml/0.2ml

產(chǎn)品價格:請

性 狀:Lyophilized or Liquid

濃 度:1mg/1ml

亞 型:IgG

貯 存:貯存于-20℃.

抗體來源:本公司抗體有兔來源和鼠來源等

克隆類型:兔來源為多抗,鼠來源為單抗

產(chǎn)品類型:一抗

此抗體本公司有單抗和多抗,可用于免疫組化(IHC),免疫印跡(WB),酶聯(lián)免疫(ELISA),IF、IP、流式細(xì)胞術(shù)等實驗(可來電索取說明)

此產(chǎn)品本公司有標(biāo)記的一抗出售,相關(guān)標(biāo)記有:Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記


Anti-Pokemon/ZBTB7抗體,撲克蒙蛋白抗體產(chǎn)品介紹:Pokemon, the POK erythroid myeloid ontogenic factor, not only regulates the expression of many genes, but also plays an important role in cell tumorigenesis. To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, its 5'-upstream region was cloned and analyzed. Transient analysis revealed that the Pokemon promoter is constitutive. Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, whereas the POS-D element was mainly responsible for its strong activity. Electrophoretic mobility shift assays suggested that the NEG-U, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro. Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter. Moreover, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate. Taken together, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy.

保存條件:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

重要提示: 本產(chǎn)品提供僅供研究使用,不用于人類治療或診斷.


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